Acute myeloid leukemia with mutated NPM1

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Acute myeloid leukemia with mutated NPM1

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Author: Elizabeth Courville
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with mutated NPM1
Published Date: 09/16/2015

There is a marked leukocytosis with blasts comprising the majority of circulating peripheral blood leukocytes. The blasts are medium to large in size and have an elevated nuclear:cytoplasmic ratio. The nuclear chromatin is fine and there are prominent nucleoli.

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