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T-LGL (CD8)

T-LGL (CD8)
#00061347
Author: Timothy C Carll, MD; Girish Venkataraman, MD, MBBS
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Mature T-cell Leukemias > T-cell Large Granular Lymphocytic Leukemia
Published Date: 03/23/2018

Intrasinusoidal CD8 T-cells

 

T-cell large granular lymphocyte  leukemia. This patient had underlying theumatoid arthritis with expansion of T-LGL cells progressing to a clonal proliferation. Neoplastic proliferations often harbor underlying STAT3 and STAT5B mutations

 

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