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AML-CD34

AML-CD34
#00061853
Author: Girish Venkataraman, MD, MBBS
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > AML with multilineage dysplasia
Published Date: 09/07/2018

Acute myeloid leukemia after therapy with decitabine x 2 cycles with persistent blasts expressing CD34 (small CD34+ cells) admixed with abnormal strong staining for CD34 in dysplastic megakaryocytes (on the left side).

 

Frequently, abnormal staining is seen in AML and MDS megakaryocytes for CD34 although this aberrant staining is not specific and can be seen in megaloblastic anemia and other autoimmune conditions.