Anaplastic large cell lymphoma, ALK-negative

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Anaplastic large cell lymphoma, ALK-negative

#00062243

Author: Benjamin Kaumeyer, MD; Girish Venkataraman, MD
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Cutaneous T-cell Lymphoma > Primary Cutaneous CD30-positive T-cell Lymphoproliferative disorders > Anaplastic Large Cell Lymphoma
Published Date: 03/27/2019

This is a Diff-Quik stained pleural fluid cytology specimen involved by anaplastic large cell lymphoma (ALCL). The large lymphoma cells have irregular nuclei with abundant cytoplasm and numerous cytoplasmic vacuoles. This patient also had lymph node and cutaneous involvement which showed the following immunophenotype: positive for CD3, CD4, and CD30; negative for CD5, CD7, and ALK.

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