B ALL

Author:  Katherine Calvo, MD, PhD, 01/26/2016
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Precursor Lymphoid Neoplasms > B-lymphoblastic leukemia/lymphoma > B-Lymphoblastic Leukemia/Lymphoma, not otherwise specified
Published Date: 01/26/2016
4 year old male with anemia and thrombocytopenia
Peripheral Blood 4 year old male with anemia and thrombocytopenia andblasts on the peripheral smear
B-ALL-CD-34-negative-Peripheral-Blood
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Marrow Aspirate The aspirate was 99% blasts.
B-ALL-CD-34-negative-Aspirate
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Marrow Biopsy Core bone marrow biopsy:  100% cellularity with marrow replaced by blasts
B-ALL-CD-34-negative-Marrow-biopsy
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Special Stains Special stains as shown.
B-ALL-CD-34-negative-Special-Stains
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Flow cytometry
Flow cytometry analysis of the peripheral blood revealed a blast population that was positive CD19 and CD10; largely negative for CD34; and negative for CD45, CD20, CD13, and surface light chains.  Diagnosis:  B lymphoblastic leukemia.
B-ALL-CD-34-negative-Flow-Cytometry
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